BDBM794053 5-[1-methyl-3-[(1R)-2,2,2-trifluoro-1-phenyl-ethoxy]pyrazolo[3,4-c]pyridazin-5-yl]-1H-pyrimidine-2,4-dione and 5-[1-methyl-3-[(1S)-2,2,2-trifluoro-1-phenyl-ethoxy]pyrazolo[3,4-c]pyridazin-5-yl]-1H-pyrimidine-2,4-dione::US20260055113, Example 30A

SMILES Cn1nc(O[C@@H](c2ccccc2)C(F)(F)F)c2cc(-c3c[nH]c(=O)[nH]c3=O)nnc21

InChI Key InChIKey=NDZSHFGRTXLLEQ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 794053   

Target5'-nucleotidase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 794053BDBM794053(5-[1-methyl-3-[(1R)-2,2,2-trifluoro-1-phenyl-ethox...)
Affinity DataIC50: 0.150nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details US Patent