BDBM794060 5-(3-cyclobutylisoxazolo[5,4-c]pyridazin-5-yl)-1H-pyrimidine-2,4-dione::US20260055113, Example 46

SMILES O=c1[nH]cc(-c2cc3c(C4CCC4)noc3nn2)c(=O)[nH]1

InChI Key InChIKey=RGLNMVLJITTXQU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 794060   

Target5'-nucleotidase(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 794060BDBM794060(5-(3-cyclobutylisoxazolo[5,4-c]pyridazin-5-yl)-1H-...)
Affinity DataIC50: 2nMAssay Description:The c-Kit mutant D816V inhibitors were assessed using an engineered BaF3-FL KIT D816V or BaF3-FL KIT V560G/D816V cell line. The BaF3-FL KIT D816V cel...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/9/2026
Entry Details US Patent