BDBM794252 3- (difluoromethoxy)- 4-(3-methyl-4- methylsulfonyl- phenyl)-1H- pyrazolo[3,4- c]pyridine-5- carbonitrile::US12565497, Example 52

SMILES Cc1cc(-c2c(C#N)ncc3[nH]nc(OC(F)F)c23)ccc1S(C)(=O)=O

InChI Key

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 794252   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 794252BDBM794252(3- (difluoromethoxy)- 4-(3-methyl-4- methylsulfony...)
Affinity DataIC50: 13nMAssay Description:NMDA receptors are ion channels that are highly permeable to Ca2+ ions, rendering it possible to monitor NMDA receptor function using cell-based calc...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/13/2026
Entry Details US Patent