BDBM794273 3-methoxy-4-(3-methyl-4-(methylsulfonyl)phenyl)-1H-indazole-5-carbonitrile & 3-(difluoromethoxy)-4-(3-methyl-4-(methylsulfonyl)phenyl)-1H-indazole-5-carbonitrile::US12565497, Example 68

SMILES COc1n[nH]c2ccc(C#N)c(-c3ccc(S(C)(=O)=O)c(C)c3)c12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 794273   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 794273BDBM794273(3-methoxy-4-(3-methyl-4-(methylsulfonyl)phenyl)-1H...)
Affinity DataIC50: 13nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/13/2026
Entry Details US Patent