BDBM794293 3-cyclopropyl-6-fluoro-N-methyl-4-(3-methyl-4-(methylsulfonyl)phenyl)-1H-indazole-5-carboxamide & 3-cyclopropyl-4-(4-cyclopropylsulfonyl-3-methyl-phenyl)-N-methyl-1H-pyrazolo[3,4-c]pyridine-5-carboxamide::US12565497, Example 88

SMILES CNC(=O)c1c(F)cc2[nH]nc(C3CC3)c2c1-c1ccc(S(C)(=O)=O)c(C)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 794293   

TargetS-adenosylmethionine synthase isoform type-2(Human)
Hoffmann-La Roche

US Patent
LigandChemical structure of BindingDB Monomer ID 794293BDBM794293(3-cyclopropyl-6-fluoro-N-methyl-4-(3-methyl-4-(met...)
Affinity DataIC50: 13nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/13/2026
Entry Details US Patent