BDBM794329 Synthesis of 4-isobutyl-3-methyl-1-(2-methyl-4-(pyrrolo[2,1-f][1,2,4]triazin-4-yl)benzyl)piperazin-2-one ::US12565500, Compound 2

SMILES Cc1cc(-c2ncnn3cccc23)ccc1CN1CCN(CC(C)C)C(C)C1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 794329   

TargetTyrosine-protein kinase BTK(Human)
Biogen Ma

US Patent
LigandChemical structure of BindingDB Monomer ID 794329BDBM794329(Synthesis of 4-isobutyl-3-methyl-1-(2-methyl-4-(py...)
Affinity DataIC50: 510nMAssay Description:For high throughput measurement of agonist-evoked increases in intracellular calcium, CHO-K1 cells stably expressing muscarinic receptors were plated...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/13/2026
Entry Details US Patent