BDBM794432 2-amino-4-[3-methyl-5-(1-methylindazol-5-yl)-2-(2-prop-2-enoyl-2-azaspiro[3.3]heptan-6-yl)imidazol-4-yl]benzothiophene-3-carbonitrile::US20260060961, Example 36

SMILES C=CC(=O)N1CC2(CC(c3nc(-c4ccc5c(cnn5C)c4)c(-c4cccc5sc(N)c(C#N)c45)n3C)C2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 794432   

TargetGTPase KRas [G12C](Human)
Jazz Pharmaceuticals Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 794432BDBM794432(2-amino-4-[3-methyl-5-(1-methylindazol-5-yl)-2-(2-...)
Affinity DataIC50: 5.50E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/12/2011
Entry Details
PCBioAssay