BDBM794435 1-[6-[5-[5-hydroxy-2-(trifluoromethyl)phenyl]-1-methyl-4-(1-methylindazol-5-yl)imidazol-2-yl]-2-azaspiro[3.3]heptan-2-yl]prop-2-en-1-one::US20260060961, Example 39

SMILES C=CC(=O)N1CC2(CC(c3nc(-c4ccc5c(cnn5C)c4)c(-c4cc(O)ccc4C(F)(F)F)n3C)C2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 794435   

TargetGTPase KRas [G12C](Human)
Jazz Pharmaceuticals Ireland

US Patent
LigandChemical structure of BindingDB Monomer ID 794435BDBM794435(1-[6-[5-[5-hydroxy-2-(trifluoromethyl)phenyl]-1-me...)
Affinity DataIC50: 1.00E+3nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/12/2011
Entry Details
PCBioAssay