BDBM794586 US20260062387, Example 117

SMILES COc1cc(-c2c3c(C(F)F)cc(-c4cnn(CC5(O)CCC5)c4)cc3nn2C)cc(OC(F)F)c1C(=O)N[C@@H]1CC1(F)F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 794586   

TargetSerine/threonine-protein kinase SIK3(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 794586BDBM794586(US20260062387, Example 117)
Affinity DataIC50: 1nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
TargetSerine/threonine-protein kinase SIK2(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 794586BDBM794586(US20260062387, Example 117)
Affinity DataIC50: 9.30nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
TargetSerine/threonine-protein kinase SIK1(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 794586BDBM794586(US20260062387, Example 117)
Affinity DataIC50: 12.5nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay