BDBM794630 US20260062387, Example 161

SMILES COc1cc(-c2cnn(C)c2)cc2nn(C)c(-c3cc(OC(F)F)c4c(c3)C(C)CNC4=O)c12

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 794630   

TargetSerine/threonine-protein kinase SIK2(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 794630BDBM794630(US20260062387, Example 161)
Affinity DataIC50: 1.30nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
TargetSerine/threonine-protein kinase SIK1(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 794630BDBM794630(US20260062387, Example 161)
Affinity DataIC50: 5.60nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay
TargetSerine/threonine-protein kinase SIK3(Human)
Mitsubishi Tanabe Pharma

US Patent
LigandChemical structure of BindingDB Monomer ID 794630BDBM794630(US20260062387, Example 161)
Affinity DataIC50: 10nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/8/2014
Entry Details
PCBioAssay