BDBM794684 3-Amino-7-bromo-6-chloro-4-(7-chloro-1H-indazol-4-yl)-1H-quinolin-2-one::US20260062412, Compound A27

SMILES Nc1c(-c2ccc(Cl)c3[nH]ncc23)c2cc(Cl)c(Br)cc2[nH]c1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 794684   

TargetMyelin transcription factor 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 794684BDBM794684(3-Amino-7-bromo-6-chloro-4-(7-chloro-1H-indazol-4-...)
Affinity DataIC50: 0.520nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO-OX1 or CHO-OX2 cells are seeded into black-walled clear-base 384-well plates (Costar) at a density of 20,00...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/15/2026
Entry Details US Patent

TargetMyelin transcription factor 1(Human)
Chugai Seiyaku Kabushiki Kaisha

US Patent
LigandChemical structure of BindingDB Monomer ID 794684BDBM794684(3-Amino-7-bromo-6-chloro-4-(7-chloro-1H-indazol-4-...)
Affinity DataIC50: 40nMAssay Description:NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Dr. Randal Kaufman, Univer...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/15/2026
Entry Details US Patent