BDBM795095 US20260062420, Compound IWD-005

SMILES Cn1c2c(oc1=O)C=CC(c1ccc(C[C@@H](C#N)NC(=O)[C@H]3C[C@@H]4COC[C@@H]4N3)cc1)C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 795095   

TargetDipeptidyl peptidase 1(Mouse)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 795095BDBM795095(US20260062420, Compound IWD-005)
Affinity DataIC50: 45.6nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO-OX1 or CHO-OX2 cells are seeded into black-walled clear-base 384-well plates (Costar) at a density of 20,00...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/15/2026
Entry Details US Patent

TargetDipeptidyl peptidase 1(Human)
Insmed

US Patent
LigandChemical structure of BindingDB Monomer ID 795095BDBM795095(US20260062420, Compound IWD-005)
Affinity DataIC50: 69.2nMAssay Description:Measurement of [Ca2+]i using a FLIPR: CHO-OX1 or CHO-OX2 cells are seeded into black-walled clear-base 384-well plates (Costar) at a density of 20,00...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/15/2026
Entry Details US Patent