BDBM796576 (10S,17E)-16-ethyl-8,10,12,14- tetramethyl-2,11,12,14-tetrahydro-8H- 3,5-ethenotripyrazolo[3,4-f:3'',4''-j:4$#8243;,3$#8243;- n][1,4]oxazacyclopentadecin-13(10H)- one::US20260070924, Example 23

SMILES CCc1nn(C)c2c1/C=C/c1n[nH]c3ccc(cc13)-c1cnn(C)c1O[C@@H](C)CN(C)C2=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 796576   

TargetDual specificity protein kinase CLK2(Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 796576BDBM796576((10S,17E)-16-ethyl-8,10,12,14- tetramethyl-2,11,12...)
Affinity DataIC50: 0.225nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 796576BDBM796576((10S,17E)-16-ethyl-8,10,12,14- tetramethyl-2,11,12...)
Affinity DataIC50: 0.416nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK1(Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 796576BDBM796576((10S,17E)-16-ethyl-8,10,12,14- tetramethyl-2,11,12...)
Affinity DataIC50: 0.843nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details US Patent

TargetDimer of Receptor-type tyrosine-protein kinase FLT3(Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 796576BDBM796576((10S,17E)-16-ethyl-8,10,12,14- tetramethyl-2,11,12...)
Affinity DataIC50: 0.967nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK4(Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 796576BDBM796576((10S,17E)-16-ethyl-8,10,12,14- tetramethyl-2,11,12...)
Affinity DataIC50: 1.39nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK3(Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 796576BDBM796576((10S,17E)-16-ethyl-8,10,12,14- tetramethyl-2,11,12...)
Affinity DataIC50: 5.53nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details US Patent