BDBM796578 (18E)-8,10,13,15,17-pentamethyl- 2,8,9,10,11,12,13,15-octahydro-14H- 3,5-ethenotripyrazolo[3,4-f:3'',4''-j:4$#8243;,3$#8243;- n][1,4]diazacyclohexadecin-14-one::US20260070924, Example 15

SMILES Cc1nn(C)c2c1/C=C/c1n[nH]c3ccc(cc13)-c1cnn(C)c1CN(C)CCN(C)C2=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 796578   

TargetDual specificity protein kinase CLK1(Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 796578BDBM796578((18E)-8,10,13,15,17-pentamethyl- 2,8,9,10,11,12,13...)
Affinity DataIC50: 0.157nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK2(Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 796578BDBM796578((18E)-8,10,13,15,17-pentamethyl- 2,8,9,10,11,12,13...)
Affinity DataIC50: 0.161nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK4(Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 796578BDBM796578((18E)-8,10,13,15,17-pentamethyl- 2,8,9,10,11,12,13...)
Affinity DataIC50: 0.530nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details US Patent

TargetDual specificity protein kinase CLK3(Human)
Blossomhill Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 796578BDBM796578((18E)-8,10,13,15,17-pentamethyl- 2,8,9,10,11,12,13...)
Affinity DataIC50: 2.77nMAssay Description:This cell-based assay measures the ability of compounds to inhibit forskolin stimulated cAMP in CHO-K1 cells overexpressing SSTR4. CHO-K1 cells overe...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
7/23/2026
Entry Details US Patent