BDBM796630 US9663526, Example 65::US11197867, Example 65::US10980815, Example 65::US10463675, Example 65

SMILES FC1(F)C[C@@H]1CN2[C@@H]5CC[C@H]2CN(c4ccnc(Nc3cn[nH]c3)n4)C5

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 796630   

TargetNon-receptor tyrosine-protein kinase TYK2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 796630BDBM796630(US9663526, Example 65 | US11197867, Example 65 | U...)
Affinity DataIC50: 22nMAssay Description:Compounds were added to a 384-well plate. Reaction mixtures contained 10 mM HEPES, pH 7.4, 10 mM MgCl2, 0.01% BSA, 0.0005% Tween 20, 1 mM ATP and 1 &...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK1(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 796630BDBM796630(US9663526, Example 65 | US11197867, Example 65 | U...)
Affinity DataIC50: 35nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 796630BDBM796630(US9663526, Example 65 | US11197867, Example 65 | U...)
Affinity DataIC50: 223nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent

TargetTyrosine-protein kinase JAK3(Human)
Pfizer

US Patent
LigandChemical structure of BindingDB Monomer ID 796630BDBM796630(US9663526, Example 65 | US11197867, Example 65 | U...)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
6/4/2019
Entry Details
US Patent