BDBM799 Macrocycle-containing Compound 9e::tert-butyl N-[(7S,10S,13S)-10-butyl-13-[(1R)-2-[(4-acetamidobenzene)(3-methylbutyl)sulfonamido]-1-hydroxyethyl]-8,11-dioxo-2-oxa-9,12-diazabicyclo[13.2.2]nonadeca-1(17),15,18-trien-7-yl]carbamate
SMILES CCCC[C@@H]1NC(=O)[C@H](CCCCOc2ccc(C[C@H](NC1=O)[C@H](O)CN(CCC(C)C)S(=O)(=O)c1ccc(NC(C)=O)cc1)cc2)NC(=O)OC(C)(C)C
InChI Key InChIKey=MVEFGMVKYUWSQO-SKXFTCKDSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 799
TargetDimer of Gag-Pol polyprotein [491-589,Q7K,L33I,C67B,C95B](Human immunodeficiency virus type 1)
University of Queensland
University of Queensland
Affinity DataKi: 7.5nM ΔG°: -11.5kcal/molepH: 6.5 T: 37°CAssay Description:Inhibition constants were determined by a fluorometric assay. Ki values were calculated from either Dixon plots or Henderson plots in cases where the...More data for this Ligand-Target Pair