BDBM799278 (4-(Trifluoromethyl)cyclohexyl)methyl ((2S)-4-methyl-1-oxo-1-(((2S)-1-oxo-3-(2-oxopyrrolidin-3-yl)propan-2-yl)amino)pentan-2-yl)carbamate::US12583820, Compound 6b

SMILES CC(C)C[C@H](NC(=O)OCC1CCC(C(F)(F)F)CC1)C(=O)N[C@H](C=O)CC1CCNC1=O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 799278   

TargetReplicase polyprotein 1a(2019-nCoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799278BDBM799278((4-(Trifluoromethyl)cyclohexyl)methyl ((2S)-4-meth...)
Affinity DataIC50: 200nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799278BDBM799278((4-(Trifluoromethyl)cyclohexyl)methyl ((2S)-4-meth...)
Affinity DataIC50: 330nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetOrf1a protein(MERS-CoV)
Kansas State University Research Foundation; Wichita State University; University of Iowa Research Foundation

US Patent
LigandChemical structure of BindingDB Monomer ID 799278BDBM799278((4-(Trifluoromethyl)cyclohexyl)methyl ((2S)-4-meth...)
Affinity DataIC50: 2.50E+4nMAssay Description:This example demonstrates the ability of the compounds of the disclosure to degrade a Nano luciferase-BRO9 fusion protein in a cell-based degradation...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent