BDBM79945 US20250388575, Compound I-30

SMILES CCS(=O)(=O)Nc1ccc(OCC(OCCOC2CCN(c3ccc(C(=O)N[C@H]4CC[C@H](Oc5ccc(C#N)c(Cl)c5)CC4)nn3)CC2)C2CC2)c(-c2cn(C)c(=O)c3[nH]ccc23)c1

InChI Key InChIKey=VHBRMSLGESEWMS-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 79945   

TargetBromodomain-containing protein 4 [58-164](Human)
Halda Therapeutics OpCo

US Patent
LigandChemical structure of BindingDB Monomer ID 79945BDBM79945(US20250388575, Compound I-30)
Affinity DataKd:  55nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent

TargetBromodomain-containing protein 4 [353-454](Human)
Halda Therapeutics OpCo

US Patent
LigandChemical structure of BindingDB Monomer ID 79945BDBM79945(US20250388575, Compound I-30)
Affinity DataKd:  55nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/6/2026
Entry Details
US Patent