BDBM799473 US12583855, Example 2

SMILES Cn1cc(-c2cc(-c3ccc(N4CCN(C(=O)C5=CCCC5)CC4)nc3)c3c(C#N)cnn3c2)cn1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 799473   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Shouyao Holdings (Beijing) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 799473BDBM799473(US12583855, Example 2)
Affinity DataIC50: 0.108nMAssay Description:Cytokinesis is a cell-based assay to assess nonmuscle myosin II function, performed using COS7 cells. The assay is run in a 96 well plate, with 2,000...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret [V804M](Human)
Shouyao Holdings (Beijing) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 799473BDBM799473(US12583855, Example 2)
Affinity DataIC50: 0.906nMAssay Description:Cytokinesis is a cell-based assay to assess nonmuscle myosin II function, performed using COS7 cells. The assay is run in a 96 well plate, with 2,000...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Shouyao Holdings (Beijing) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 799473BDBM799473(US12583855, Example 2)
Affinity DataIC50: 13.4nMAssay Description:Cytokinesis is a cell-based assay to assess nonmuscle myosin II function, performed using COS7 cells. The assay is run in a 96 well plate, with 2,000...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent