BDBM799529 US12583855, Example 51

SMILES CSc1cccc(CN2CCN(c3ccc(-c4cc(-c5cnn(C)c5)cn5ncc(C#N)c45)cn3)CC2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 799529   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Shouyao Holdings (Beijing) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 799529BDBM799529(US12583855, Example 51)
Affinity DataIC50: 0.328nMAssay Description:Cytokinesis is a cell-based assay to assess nonmuscle myosin II function, performed using COS7 cells. The assay is run in a 96 well plate, with 2,000...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Shouyao Holdings (Beijing) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 799529BDBM799529(US12583855, Example 51)
Affinity DataIC50: 6.20nMAssay Description:Cytokinesis is a cell-based assay to assess nonmuscle myosin II function, performed using COS7 cells. The assay is run in a 96 well plate, with 2,000...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent