BDBM799569 4-(5-(6-(4-(methylsulfonyl)benzyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyrazin-2-yl)-6-(1-(difluoromethyl)-1Hpyrazol-4-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile::US12583855, Example 70

SMILES CS(=O)(=O)c1ccc(CN2C3CC2CN(c2cnc(-c4cc(-c5cnn(C(F)F)c5)cn5ncc(C#N)c45)cn2)C3)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 799569   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Shouyao Holdings (Beijing) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 799569BDBM799569(4-(5-(6-(4-(methylsulfonyl)benzyl)-3,6-diazabicycl...)
Affinity DataIC50: 0.324nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase receptor Ret [V804M](Human)
Shouyao Holdings (Beijing) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 799569BDBM799569(4-(5-(6-(4-(methylsulfonyl)benzyl)-3,6-diazabicycl...)
Affinity DataIC50: 2.52nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent

TargetVascular endothelial growth factor receptor 2(Human)
Shouyao Holdings (Beijing) Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 799569BDBM799569(4-(5-(6-(4-(methylsulfonyl)benzyl)-3,6-diazabicycl...)
Affinity DataIC50: 55.7nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent