BDBM799713 US12583853, Compound Example 3::2-(1-(1H-pyrrolo[2,3-b]pyridin-5-yl) vinyl)-4-(4-((4′-chloro-5,5-dimethyl-3,4,5,6-tetrahydro-[1,1′-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((3-nitro-4-(((tetrahydro-2H-pyran-4-yl)methyl)amino)phenyl)sulfonyl)benzamide

SMILES C=C(C2=CN=C1NC=CC1C2)c6cc(N5CCN(CC4=C(c3ccc(Cl)cc3)CC(C)(C)CC4)CC5)ccc6C(=O)NS(=O)(=O)c8ccc(NCC7CCOCC7)c([N+](=O)[O-])c8

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 799713   

TargetApoptosis regulator Bcl-2(Human)
Newave Pharmaceutical

US Patent
LigandChemical structure of BindingDB Monomer ID 799713BDBM799713(US12583853, Compound Example 3 | 2-(1-(1H-pyrrolo[...)
Affinity DataIC50: 1.30nMAssay Description:Cytokinesis is a cell-based assay to assess nonmuscle myosin II function, performed using COS7 cells. The assay is run in a 96 well plate, with 2,000...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/3/2026
Entry Details
US Patent