BDBM800244 (E)-N-hydroxy-3-(4-(((3-hydroxy-4-oxo-2-(2-(trifluoromethyl)phenyl)-1,4-dihydroquinolin-7-yl)amino)methyl)phenyl)acrylamide::US20260085046, Compound Cpd052

SMILES O=C(/C=C/c1ccc(CNc2ccc3c(=O)c(O)c(-c4ccccc4C(F)(F)F)[nH]c3c2)cc1)NO

InChI Key InChIKey=MFNSZJXGZFBSCB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 800244   

TargetHistone deacetylase 1(Human)
Taiwanj Pharmaceuticals Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 800244BDBM800244((E)-N-hydroxy-3-(4-(((3-hydroxy-4-oxo-2-(2-(triflu...)
Affinity DataIC50: 500nMAssay Description:The pan-HDAC in vitro activity is detected by HDAC-Glo™/II Assay and Screening System (#G6420, Promega, WI, USA). This system is single-reagent-addit...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent