BDBM800252 N-hydroxy-3-(4-(N-(3-hydroxy-4-oxo-2-(2-(trifluoromethyl)phenyl)-1,4-dihydroquinolin-7-yl)sulfamoyl)phenyl)propanamide::US20260085046, Compound Cpd059

SMILES O=C(CCc1ccc(S(=O)(=O)Nc2ccc3c(=O)c(O)c(-c4ccccc4C(F)(F)F)[nH]c3c2)cc1)NO

InChI Key InChIKey=ACVYQWYMGGRGNU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 800252   

TargetHistone deacetylase 1(Human)
Taiwanj Pharmaceuticals Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 800252BDBM800252(N-hydroxy-3-(4-(N-(3-hydroxy-4-oxo-2-(2-(trifluoro...)
Affinity DataIC50: 500nMAssay Description:The pan-HDAC in vitro activity is detected by HDAC-Glo™/II Assay and Screening System (#G6420, Promega, WI, USA). This system is single-reagent-addit...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent