BDBM800270 (E)-3-(2-(2-fluorophenyl)-3-hydroxy-4-oxo-1,4-dihydroquinolin-6-yl)-N-hydroxyacrylamide::US20260085046, Compound Cpd066

SMILES O=C(/C=C/c1ccc2[nH]c(-c3ccccc3F)c(O)c(=O)c2c1)NO

InChI Key InChIKey=SSWBNWLDVTXMMN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 800270   

TargetHistone deacetylase 1(Human)
Taiwanj Pharmaceuticals Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 800270BDBM800270((E)-3-(2-(2-fluorophenyl)-3-hydroxy-4-oxo-1,4-dihy...)
Affinity DataIC50: 100nMAssay Description:The pan-HDAC in vitro activity is detected by HDAC-Glo™/II Assay and Screening System (#G6420, Promega, WI, USA). This system is single-reagent-addit...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent