BDBM800319 (S)-8-methoxy-3-methyl-6-(6-(1-methyl-1H-pyrazol-4-yl)benzofuran-3-yl)-2-(2,2,2-trifluoroethyl)-3,4-dihydroisoquinolin-1 (2H)-one::US20260085053, Example 29A

SMILES COC5C=C(c2coc3cc(c1cnn(C)c1)ccc23)C=C4C[C@H](C)N(CC(F)(F)F)C(=O)C45

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 800319   

TargetSerine/threonine-protein kinase SIK2(Human)
Beone Medicines I

US Patent
LigandChemical structure of BindingDB Monomer ID 800319BDBM800319((S)-8-methoxy-3-methyl-6-(6-(1-methyl-1H-pyrazol-4...)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK3 [59-365](Human)
Beone Medicines I

US Patent
LigandChemical structure of BindingDB Monomer ID 800319BDBM800319((S)-8-methoxy-3-methyl-6-(6-(1-methyl-1H-pyrazol-4...)
Affinity DataIC50: 42nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK1 [1-303](Human)
Beone Medicines I

US Patent
LigandChemical structure of BindingDB Monomer ID 800319BDBM800319((S)-8-methoxy-3-methyl-6-(6-(1-methyl-1H-pyrazol-4...)
Affinity DataIC50: 216nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent