BDBM800336 3-(3-(4-(3-(8-(difluoromethoxy)-1-oxo-2-(2,2,2-trifluoroethyl)-1,2,3,4-tetrahydroisoquinolin-6-yl)benzofuran-6-yl)-1H-pyrazol-1-yl) azetidin-1-yl) propanenitrile ::US20260085053, Example 45

SMILES N#CCCN1CC(n2cc(-c3ccc4c(-c5cc6c(c(OC(F)F)c5)C(=O)N(CC(F)(F)F)CC6)coc4c3)cn2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 800336   

TargetSerine/threonine-protein kinase SIK2(Human)
Beone Medicines I

US Patent
LigandChemical structure of BindingDB Monomer ID 800336BDBM800336(3-(3-(4-(3-(8-(difluoromethoxy)-1-oxo-2-(2,2,2-tri...)
Affinity DataIC50: 9.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK3 [59-365](Human)
Beone Medicines I

US Patent
LigandChemical structure of BindingDB Monomer ID 800336BDBM800336(3-(3-(4-(3-(8-(difluoromethoxy)-1-oxo-2-(2,2,2-tri...)
Affinity DataIC50: 28nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK1 [1-303](Human)
Beone Medicines I

US Patent
LigandChemical structure of BindingDB Monomer ID 800336BDBM800336(3-(3-(4-(3-(8-(difluoromethoxy)-1-oxo-2-(2,2,2-tri...)
Affinity DataIC50: 560nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent