BDBM800339 8-(difluoromethoxy)-6-(6-(1-(pyrrolidin-3-yl)-1H-pyrazol-4-yl)benzofuran-3-yl)-2-(2,2,2-trifluoroethyl)-3,4-dihydroisoquinolin-1 (2H)-one ::US20260085053, Example 48

SMILES O=C1c2c(cc(-c3coc4cc(-c5cnn(C6CCNC6)c5)ccc34)cc2OC(F)F)CCN1CC(F)(F)F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 800339   

TargetSerine/threonine-protein kinase SIK2(Human)
Beone Medicines I

US Patent
LigandChemical structure of BindingDB Monomer ID 800339BDBM800339(8-(difluoromethoxy)-6-(6-(1-(pyrrolidin-3-yl)-1H-p...)
Affinity DataIC50: 11nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK3 [59-365](Human)
Beone Medicines I

US Patent
LigandChemical structure of BindingDB Monomer ID 800339BDBM800339(8-(difluoromethoxy)-6-(6-(1-(pyrrolidin-3-yl)-1H-p...)
Affinity DataIC50: 63nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK1 [1-303](Human)
Beone Medicines I

US Patent
LigandChemical structure of BindingDB Monomer ID 800339BDBM800339(8-(difluoromethoxy)-6-(6-(1-(pyrrolidin-3-yl)-1H-p...)
Affinity DataIC50: 524nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent