BDBM800346 2-(8-(difluoromethoxy)-6-(6-(1-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl)benzofuran-3-yl)-1-oxo-3,4-dihydroisoquinolin-2 (1H)-yl) acetonitrile ::US20260085053, Example 55

SMILES CN1CCC(n2cc(-c3ccc4c(-c5cc6c(c(OC(F)F)c5)C(=O)N(CC#N)CC6)coc4c3)cn2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 800346   

TargetSerine/threonine-protein kinase SIK2(Human)
Beone Medicines I

US Patent
LigandChemical structure of BindingDB Monomer ID 800346BDBM800346(2-(8-(difluoromethoxy)-6-(6-(1-(1-methylpiperidin-...)
Affinity DataIC50: 3.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK3 [59-365](Human)
Beone Medicines I

US Patent
LigandChemical structure of BindingDB Monomer ID 800346BDBM800346(2-(8-(difluoromethoxy)-6-(6-(1-(1-methylpiperidin-...)
Affinity DataIC50: 18nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK1 [1-303](Human)
Beone Medicines I

US Patent
LigandChemical structure of BindingDB Monomer ID 800346BDBM800346(2-(8-(difluoromethoxy)-6-(6-(1-(1-methylpiperidin-...)
Affinity DataIC50: 301nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent