BDBM800373 2-(difluoromethoxy)-N-((1R,2S)-2-fluorocyclopropyl)-6-methoxy-4-(6-(2-((S)-3-methoxypyrrolidin-1-yl) ethoxy)benzofuran-3-yl)benzamide ::US20260085053, Example 82

SMILES COc1cc(-c2coc3cc(OCCN4CC[C@H](OC)C4)ccc23)cc(OC(F)F)c1C(=O)N[C@@H]1C[C@@H]1F

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 800373   

TargetSerine/threonine-protein kinase SIK2(Human)
Beone Medicines I

US Patent
LigandChemical structure of BindingDB Monomer ID 800373BDBM800373(2-(difluoromethoxy)-N-((1R,2S)-2-fluorocyclopropyl...)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK3 [59-365](Human)
Beone Medicines I

US Patent
LigandChemical structure of BindingDB Monomer ID 800373BDBM800373(2-(difluoromethoxy)-N-((1R,2S)-2-fluorocyclopropyl...)
Affinity DataIC50: 57nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK1 [1-303](Human)
Beone Medicines I

US Patent
LigandChemical structure of BindingDB Monomer ID 800373BDBM800373(2-(difluoromethoxy)-N-((1R,2S)-2-fluorocyclopropyl...)
Affinity DataIC50: 1.47E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/5/2026
Entry Details
US Patent