BDBM8018 (3S,4S)-N-butyl-3-hydroxy-6-methyl-4-[(2S,3S)-3-methyl-2-[1-(naphthalen-2-yl)acetamido]pentanamido]heptanamide::(S)-3-(S)-Hydroxy-6-methyl-4-[(S)-3-methyl-2-(2-naphthalen-2-yl-acetylamino)-pentanoylamino]-heptanoic acid butylamide::3-Hydroxy-6-methyl-4-[3-methyl-2-(2-naphthalen-2-yl-acetylamino)-pentanoylamino]-heptanoic acid butylamide::CHEMBL115048::hydroxyethylamine-based inhibitor 2

SMILES CCCCNC(=O)C[C@H](O)[C@H](CC(C)C)NC(=O)[C@@H](NC(=O)Cc1ccc2ccccc2c1)C(C)CC

InChI Key InChIKey=YHTKRGDAFFBWEU-BGRUSPQTSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 8018   

TargetPlasmepsin II(Plasmodium falciparum)
Uppsala University

LigandPNGBDBM8018((3S,4S)-N-butyl-3-hydroxy-6-methyl-4-[(2S,3S)-3-me...)
Affinity DataKi:  50nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin D(Human)
Uppsala University

LigandPNGBDBM8018((3S,4S)-N-butyl-3-hydroxy-6-methyl-4-[(2S,3S)-3-me...)
Affinity DataKi:  320nMAssay Description:Enzyme activities were assayed by monitoring the hydrolysis of substrate in the presence or absence of inhibitor compounds. The hydrolysis was record...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlasmepsin II(Plasmodium falciparum)
Uppsala University

LigandPNGBDBM8018((3S,4S)-N-butyl-3-hydroxy-6-methyl-4-[(2S,3S)-3-me...)
Affinity DataIC50:  50nMAssay Description:Inhibitory concentration for Plasmodium falciparum plasmepsin-2 .Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin D(Human)
Uppsala University

LigandPNGBDBM8018((3S,4S)-N-butyl-3-hydroxy-6-methyl-4-[(2S,3S)-3-me...)
Affinity DataIC50:  320nMAssay Description:Inhibitory concentration against Human cathepsin DChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed