BDBM801815 (Z)-N-(3-(2-methoxy-5-(methoxycarbonyl)-4-propiolamidophenoxy)propyl)benzimidic acid::US12605353, Compound 66

SMILES C#CC(=O)Nc1cc(OC)c(OCCC/N=C(\O)c2ccccc2)cc1C(=O)OC

InChI Key InChIKey=HJESWRGJIPPLSR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 801815   

TargetProtein disulfide-isomerase A4(Human)
Academia Sinica

US Patent
LigandChemical structure of BindingDB Monomer ID 801815BDBM801815((Z)-N-(3-(2-methoxy-5-(methoxycarbonyl)-4-propiola...)
Affinity DataIC50: 4.40nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent