BDBM801843 US12605369, Compound 19

SMILES COc1nc(NC(=O)C2CCc3cc(C#N)ccc32)ccc1C[C@H]1COC(=O)N1

InChI Key InChIKey=VRWFBZGETGJXAS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 801843   

TargetDNA polymerase(HHV-3)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 801843BDBM801843(US12605369, Compound 19)
Affinity DataIC50: 7nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDNA polymerase(HHV-5)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 801843BDBM801843(US12605369, Compound 19)
Affinity DataIC50: 10nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent