BDBM801844 US12605369, Compound 20

SMILES COc1nc(N2CCC(c3ccc(C#N)cc3)C2=O)ccc1C[C@H]1COC(=O)N1

InChI Key InChIKey=BTFNQQNECWCUFZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 801844   

TargetDNA polymerase(HHV-3)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 801844BDBM801844(US12605369, Compound 20)
Affinity DataIC50: 5nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetDNA polymerase(HHV-5)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 801844BDBM801844(US12605369, Compound 20)
Affinity DataIC50: 6nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent