BDBM801845 US12605369, Compound 21

SMILES COc1nc(N2CCN(c3ccc(C#N)cc3)C2=O)ccc1C[C@H]1COC(=O)N1

InChI Key InChIKey=LJWBLYOWUSWEPF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 801845   

TargetDNA polymerase(HHV-5)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 801845BDBM801845(US12605369, Compound 21)
Affinity DataIC50: 29nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent