BDBM801859 US12606540, Compound 28

SMILES CCn1c(CO)nn(-c2cc(O[C@@H](C)C(F)(F)F)c(/C(F)=C/c3cnccc3Cl)cc2F)c1=O

InChI Key InChIKey=MBJWSGRWMWRCRZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 801859   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Medshine Discovery

US Patent
LigandChemical structure of BindingDB Monomer ID 801859BDBM801859(US12606540, Compound 28)
Affinity DataIC50: 2.40nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent