BDBM801945 Production of 3-(2-amino-9-(2,6-difluorobenzyl)-9H-purin-6-yl)-2-methylbenzonitrile ::US12606564, Compound 114

SMILES Cc1c(C#N)cccc1-c1nc(N)nc2c1ncn2Cc1c(F)cccc1F

InChI Key InChIKey=BVLQGJQNRBVWPO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 801945   

TargetAdenosine receptor A2a(Human)
Ildong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 801945BDBM801945(Production of 3-(2-amino-9-(2,6-difluorobenzyl)-9H...)
Affinity DataKi:  55nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
Ildong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 801945BDBM801945(Production of 3-(2-amino-9-(2,6-difluorobenzyl)-9H...)
Affinity DataKi:  6.50E+5nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent