BDBM801962 2-(3-(hydroxymethyl)-4-(7-((5-(4-methylpiperazin-1-yl)pyridin-2-yl)amino)furo[3,2-b]pyridin-5-yl)pyridin-2-yl)-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one::US12606566, Compound H08

SMILES CN1CCN(c2ccc(Nc3cc(-c4ccnc(N5CCn6c(cc7c6CC(C)(C)C7)C5=O)c4CO)nc4ccoc34)nc2)CC1

InChI Key InChIKey=DKDNAGSNMVCRJH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 801962   

TargetTyrosine-protein kinase BTK(Human)
Shanghai Synergy Pharmaceutical Sciences Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 801962BDBM801962(2-(3-(hydroxymethyl)-4-(7-((5-(4-methylpiperazin-1...)
Affinity DataIC50: 0.230nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent