BDBM801966 9-fluoro-2-(3'-(hydroxymethyl)-1-methyl-5-((5-(2-methyl-2,7-diazaspiro[3.5]nonan-7-yl)pyridin-2-yl)amino)-6-oxo-1,6-dihydro-[3,4'-bipyridin]-2'-yl)-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one::US12606566, Compound H12

SMILES CN1CC2(CCN(c3ccc(Nc4cc(-c5ccnc(N6CCn7c8c(c(F)c7C6=O)CC(C)(C)C8)c5CO)cn(C)c4=O)nc3)CC2)C1

InChI Key InChIKey=XSZZWSHTKAULKA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 801966   

TargetTyrosine-protein kinase BTK(Human)
Shanghai Synergy Pharmaceutical Sciences Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 801966BDBM801966(9-fluoro-2-(3'-(hydroxymethyl)-1-methyl-5-((5-(2-m...)
Affinity DataIC50: 0.490nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
8/31/2026
Entry Details
US Patent