BDBM802042 1-[5-(benzyloxy)-1-(cyclohexylmethyl)-1H-pyrazol-3-yl]-N-(2H3)methyl(2H2)methanamine::US20260108494, Example 493

SMILES [2H]C([2H])([2H])NC([2H])([2H])c1cc(OCc2ccccc2)n(CC2CCCCC2)n1

InChI Key InChIKey=KRMVDUWYWGAWOH-HGSMBRELSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 802042   

TargetSodium-dependent serotonin transporter(Human)
Neuroinnovatech

US Patent
LigandChemical structure of BindingDB Monomer ID 802042BDBM802042(1-[5-(benzyloxy)-1-(cyclohexylmethyl)-1H-pyrazol-3...)
Affinity DataKi:  1.10nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Neuroinnovatech

US Patent
LigandChemical structure of BindingDB Monomer ID 802042BDBM802042(1-[5-(benzyloxy)-1-(cyclohexylmethyl)-1H-pyrazol-3...)
Affinity DataKi:  2.30nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Neuroinnovatech

US Patent
LigandChemical structure of BindingDB Monomer ID 802042BDBM802042(1-[5-(benzyloxy)-1-(cyclohexylmethyl)-1H-pyrazol-3...)
Affinity DataKi:  7.20nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent