BDBM802046 1-[1-(cyclohexylmethyl)-5-{[(2,5-difluorophenyl)(2H2)methyl]oxy}-1H-pyrazol-3-yl]-N-methylmethanamine::US20260108494, Example 497

SMILES [2H]C([2H])(Oc1cc(CNC)nn1CC1CCCCC1)c1cc(F)ccc1F

InChI Key InChIKey=NKGXNTZNACGEOG-KLTYLHELSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 802046   

TargetSodium-dependent serotonin transporter(Human)
Neuroinnovatech

US Patent
LigandChemical structure of BindingDB Monomer ID 802046BDBM802046(1-[1-(cyclohexylmethyl)-5-{[(2,5-difluorophenyl)(2...)
Affinity DataKi:  0.320nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2A(Human)
Neuroinnovatech

US Patent
LigandChemical structure of BindingDB Monomer ID 802046BDBM802046(1-[1-(cyclohexylmethyl)-5-{[(2,5-difluorophenyl)(2...)
Affinity DataKi:  2.40nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent

Target5-hydroxytryptamine receptor 2C(Human)
Neuroinnovatech

US Patent
LigandChemical structure of BindingDB Monomer ID 802046BDBM802046(1-[1-(cyclohexylmethyl)-5-{[(2,5-difluorophenyl)(2...)
Affinity DataKi:  2.60nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent