BDBM802064 (2S,4R)-1-((S)-5-acetyl-7,7- dimethyl-5,6,7,8-tetrahydro- 4H-[1,2,3]triazolo[1,5-a][1,4] diazepine-8-carbonyl)-4- hydroxy-N-((S)-1-(4-(4-meth- ylthiazol-5-yl)phenyl)ethyl)- pyrrolidine-2-carboxamide::US20260108613, Compound A8

SMILES CC(=O)N1Cc2cnnn2[C@H](C(=O)N2C[C@H](O)C[C@H]2C(=O)N[C@@H](C)c2ccc(-c3scnc3C)cc2)C(C)(C)C1

InChI Key InChIKey=WOHBCPFWBDMTBN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802064   

Targetvon Hippel-Lindau disease tumor suppressor(Human)
University of Michigan

US Patent
LigandChemical structure of BindingDB Monomer ID 802064BDBM802064((2S,4R)-1-((S)-5-acetyl-7,7- dimethyl-5,6,7,8-tetr...)
Affinity DataIC50: 8.40nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent