BDBM802345 6-{7-methoxyimidazo[1,2-a]pyridin-3-yl}-N-{[5-(1-methyl-1H-pyrazol-4-yl)thiophen-2-yl]methyl}pyrimidin-4-amine::US20260109697, Compound A36

SMILES COc1ccn2c(-c3cc(NCc4ccc(-c5cnn(C)c5)s4)ncn3)cnc2c1

InChI Key InChIKey=WEJJUKQJXAAADT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802345   

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 802345BDBM802345(6-{7-methoxyimidazo[1,2-a]pyridin-3-yl}-N-{[5-(1-m...)
Affinity DataIC50: 4.20nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent