BDBM802376 (6-{7-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-imidazo[1,2-a]pyridin-3-yl}-pyrimidin-4-yl)-(4-[1,2,3]triazol-1-yl-benzyl)-amine::US20260109697, Compound A67

SMILES CN1CCN(CCOc2ccn3c(-c4cc(NCc5ccc(-n6ccnn6)cc5)ncn4)cnc3c2)CC1

InChI Key InChIKey=MTIPTQXJHWRCNM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802376   

TargetMast/stem cell growth factor receptor Kit [V654A](Human)
Merck Patent

US Patent
LigandChemical structure of BindingDB Monomer ID 802376BDBM802376((6-{7-[2-(4-Methyl-piperazin-1-yl)-ethoxy]-imidazo...)
Affinity DataIC50: 4.80nMAssay Description:JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...More data for this Ligand-Target Pair
Target InfoPDB
GoogleScholar
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/2/2026
Entry Details
US Patent