BDBM802709 N5-((5-(difluoromethyl)-1- methyl-1H-1,2,3-triazol-4- yl)methyl)-1-methyl-1H- benzo[d]imidazole-2,5- diamine::US20260109709, Example 1-77

SMILES Cn1nnc(CNc2ccc3c(c2)nc(N)n3C)c1C(F)F

InChI Key InChIKey=YFEDQBGUVUUTIE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 802709   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 802709BDBM802709(N5-((5-(difluoromethyl)-1- methyl-1H-1,2,3-triazol...)
Affinity DataIC50: 545nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Mirati Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 802709BDBM802709(N5-((5-(difluoromethyl)-1- methyl-1H-1,2,3-triazol...)
Affinity DataIC50: 546nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent