BDBM802860 US12612408, Compound I-31

SMILES C=CCn1c(=O)c2cnc(Nc3ccc(C4CC(N(C)C)C4)cc3)nc2n1-c1cccc(C(C)(C)O)n1

InChI Key InChIKey=CWJPWAGQXOWGCX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802860   

TargetWee1-like protein kinase(Human)
Shanghai Pharmaceuticals Holding Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 802860BDBM802860(US12612408, Compound I-31)
Affinity DataIC50: 2.05nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/8/2026
Entry Details
US Patent