BDBM803176 US20260116881, Compound 325

SMILES CCS(=O)(=O)Nc1ccc2c(c1)N1CCC(C/C=C/CCNc3nc(ccc3-n3cc(C4CCCCN4)cn3)NC2=O)CC1

InChI Key InChIKey=UTLKGNUFJPURLV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 803176   

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803176BDBM803176(US20260116881, Compound 325)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent