BDBM803189 US20260116881, Compound 338

SMILES O=C1Nc2ccc(-n3cc(N4CCOCC4)cn3)c(n2)NCC/C=C/CC2CCN(CC2)c2cc(NS(=O)(=O)C3(CO)CC3)ccc21

InChI Key InChIKey=BWSJSWVLOMLLEU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 803189   

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803189BDBM803189(US20260116881, Compound 338)
Affinity DataIC50: 100nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent