BDBM803296 US20260116881, Compound 445

SMILES CCS(=O)(=O)c1ccc2c(c1)N1CCC(C/C=C/CCNc3nc(ccc3-n3cc(C4(C#N)CC4)cn3)NC2=O)CC1

InChI Key InChIKey=OFDPDZBHUOFHPS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 803296   

TargetKinesin-like protein KIF18A(Human)
Iambic Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 803296BDBM803296(US20260116881, Compound 445)
Affinity DataIC50: 100nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/29/2021
Entry Details
US Patent