BDBM803545 US20260116884, Compound C026

SMILES CCN1CCC(n2cc(-c3c[nH]c4ncc(-c5ccc(N6CCN(C(=O)CCCCCNc7cccc8c7C(=O)N(C7CCC(=O)NC7=O)C8=O)CC6)nc5)nc34)cn2)CC1

InChI Key InChIKey=JKDLIDYYKLYGLV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 803545   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Hangzhou Zhongmeihuadong Pharmaceutical Co.

US Patent
LigandChemical structure of BindingDB Monomer ID 803545BDBM803545(US20260116884, Compound C026)
Affinity DataIC50: 1.60nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/9/2026
Entry Details
US Patent